High-affinity glucose transport in Saccharomyces cerevisiae is under general glucose repression control
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چکیده
منابع مشابه
Glucose repression in Saccharomyces cerevisiae
Glucose is the primary source of energy for the budding yeast Saccharomyces cerevisiae. Although yeast cells can utilize a wide range of carbon sources, presence of glucose suppresses molecular activities involved in the use of alternate carbon sources as well as it represses respiration and gluconeogenesis. This dominant effect of glucose on yeast carbon metabolism is coordinated by several si...
متن کاملThe Penicillium chrysogenum transporter PcAraT enables high-affinity, glucose-insensitive l-arabinose transport in Saccharomyces cerevisiae
Background l-Arabinose occurs at economically relevant levels in lignocellulosic hydrolysates. Its low-affinity uptake via the Saccharomyces cerevisiae Gal2 galactose transporter is inhibited by d-glucose. Especially at low concentrations of l-arabinose, uptake is an important rate-controlling step in the complete conversion of these feedstocks by engineered pentose-metabolizing S. cerevisiae s...
متن کاملRelationship between low- and high-affinity glucose transport systems of Saccharomyces cerevisiae.
The high-affinity glucose transport process in Saccharomyces cerevisiae whole cells was regulated by catabolite repression and inactivation. The low-affinity process was constitutive, and its activity was inhibited in proportion to the extent of derepression of the high-affinity process. The latter finding suggests that there is some regulatory relationship between the two processes.
متن کاملSucz Gene Expression by Glucose Repression in Saccharomyces Cerevisiae
Mutants of Saccharomyces cereoisiae with defects in sucrose or raffinose fermentation were isolated. In addition to mutations in the SUCZ structural gene for invertase, we recovered 18 recessive mutations that affected the regulation of invertase synthesis by glucose repression. These mutations included five new snfl (Sucrose ponfermenting) alleles and also defined five new complementation grou...
متن کاملGlucose repression can be alleviated by reducing glucose phosphorylation rate in Saccharomyces cerevisiae
Microorganisms commonly exhibit preferential glucose consumption and diauxic growth when cultured in mixtures of glucose and other sugars. Although various genetic perturbations have alleviated the effects of glucose repression on consumption of specific sugars, a broadly applicable mechanism remains unknown. Here, we report that a reduction in the rate of glucose phosphorylation alleviates the...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1988
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.170.10.4838-4845.1988